Does Vitamin E Repair Damaged Hair

Nearly Writer
P.5. POWAR
Dr. D. Y. Patil College of Chemist's shop,
Akurdi, Pune.44

Vitamin Eastward or Alpha-Tocopherol is fat-soluble antioxidant which supports for rebuild and repair aged tissues. Vitamin Due east exists in eight chemical forms as shown in bellow diagram

Reference Id: PHARMATUTOR-ART-2595

Effigy No.01: Various forms of Vitamin East [1]

Nutrient sources of vitamin E contain safflower, sunflower, wheat germ, palm, corn and soybean oil ,nuts, whole grain, avocado, asparagus, pumpkin, spinach and light-green, leafy vegetables. Diverse health benefits of vitamin E.
• Balances Cholesterol:
Vitamin Due east evidence cholesterol-lowering effect by inhibiting the oxidation of Cholesterol reduces the risks of atherosclerosis and other cardiovascular disorders.

• Antioxidant Activity and anticancer action:
Stops the production of reactive oxygen species (ROS) formed when fat undergoes oxidation. Due to lipophillic nature of Vitamin E it is accumulate in lipid compartment, prison cell membrane and prevent oxidation by neutralizing free radical and likewise show protective action for inflammation, and therefore help naturally slow aging in your cells and fight off health issues like heart illness[two]. Vitamin East inhibits the action of protein Kinase C, (enzyme concerned in cell proliferation, differentiation in smooth muscle cells, platelets, and monocytes. Vitamin East present in endothelial cells lining the interior surface of blood vessels are ameliorate able to resist blood-jail cell components stick to internal surface (human action every bit a anti blood clotting agent) and also release of prostacyclin from the endothelium, help for dilates claret vessels and inhibits platelet assemblage[3] . Vitamin Due east inhibits the conversion of nitrites in smoked, pickled and cured foods to nitrosamines in the stomach. Nitrosamines have been known to contribute to some forms of cancer [4]. Then Vitamin E provides protection of DNA, protein and lipids from oxidative harm.

• Anti-aging Activity :
Vitamin E helps for strengthening the capillary walls , improving moisture and elasticity, acting as a natural anti-aging and also reduces inflammation, antioxidant properties of Vitamin E helps in Anticancer activity , assist in Peel Hyper-pigmentation and anti wrinkle activity (also help in erasing action of stretch marks). Vitamin E when used equally topically increases hydratation of the stratum corneum, water-bounden capacity and reduces the harmful collagen-destroying enzyme collagenase ( i.e anti-aging belongings)[five] . Gamma tocotrienol abridged inflammatory signals that pursue UVB radiations exposure like COX-ii, interleukin-1beta, IL-half-dozen, and monocyte chemotactic poly peptide-ane[six,vii] .It also heighten cell regeneration capacity then show Anti scar , anti acne activity. It as well help for promote formation of RBC, also aid for wound healing process [viii].

• Use for Hyper pigmentation and photograph-aging:
Vitamin Due east ho-hum the production of melanin by suppressing the activity of an enzyme chosen tyrosinase [9]. And antioxidant protection gives younger looking skin

• Balances Hormones:
It able to maintain endocrine and nervous systems, it besides helps to reduce PMC syndrome.

• Useful in burn wounds and stretch marks:
Stretch marks appear due to excessive stretch of skin fibers. While the skin naturally tries to repair itself, the procedure is slowed down by the complimentary radicals. And vitamin E acts as an Antioxidant which shows constructive confronting stretch marks by supportive action in jail cell regeneration [10].

• Improves Vision:
It helps to prevent related macular degeneration (cause of blindness) impairment to retina.
• Physical endurance:
Vitamin Due east may play an important role in preventing the free radical impairment associated with endurance exercise, preventing exercise-induced lipid peroxidation (Vitamin E acts equally a chain-breaking antioxidant) [xi,12].

• Protection confronting Alzheimer's Disease:
Anti-inflammatory activity , protection against neurodegenerative disorders and dementia.[13]

• Psoriasis:
Anti-inflammatory useful in Psoriasis. Information technology causes dead skin cells to build upward in scaly, cherry-red-pink patches.

• Allowed system Protector:
Comeback in T4 function tin leads to boosting effect of immunity and helps the body fight off infection. As well act as a primary defense line for oxidative impairment as it acta s a stiff antioxidant. Vitamin E intake increases plasma vitamin E, DTH score, mitogenic response to concanavalin A (Con-A), DTH response and interleukin (IL)-two production ; and decreased prostaglandin (PG)E2 product by peripheral blood mononuclear cells (PBMCs) and decreased plasma lipid peroxide concentrations.

• Hair intendance regimen:
Vitamin E can be good support system for all your hair problems and promote pilus growth, stop hair loss. Post-obit are actions shown by Vitamin East

1. Blood Circulation improves: Vitamin East dilates the claret vessels past secretion of prostacyclin, and improves the claret flow / supply and information technology also prevents blood clotting. This activeness improves nourishment for pilus follicles and promoting hair growth ,produce thick and healthy hair. Too restore shine of hairs, human action as a pilus conditioner and give glossy, silky past production of protective , nutrient shield on hair surface[14,15] .
2. Prevents Hair Loss and premature graying : Provides physical stability to hair follicles and reduces the rate at which hair strands autumn off. Improv the oxygenation of the skin past dilation of blood vessel and increase blood flow enhances transport of needed nutrients to pilus follicles which leads to rapid hair growth and the healing/ repairing of damaged hair shafts. It also provide protection from dehydration and ultraviolet rays. Premature graying of hair is caused past oxidization of tissues and vitamin E oil helps prevent depletion of tissues, which in turn helps impede premature graying of pilus. Antioxidant activeness also forbid dissever ends of hairs[16] .
iii. Residuum for oil product: Vitamin Eastward is important for creating a protective barrier on the skin's surface and provide maintenance of sufficient oil for nourishment, maintain moisture and regulate oil production. This barrier helps lock in wet and protect from attacks of free radicals produce from pollution and smoke. Sebaceous glands producing more oil than necessary (high amount leads to itching, hair loss, dandruff , thinning hair, alopecia or alopecia and less amount of oil leads to dry scalp , dandruff, hair loss, separate ends)[17] .
four. Antioxidant Activity: Antioxidant action which show neutralizationreaction for free radicals which leads to hair damage.
5. Protection confronting sun rays: Equally vitamin E act as an antioxidant, protect confronting oxidative stress, free radicals produces during oxidation protein , fats. Harsh ultraviolet rays from the dominicus that can cause dryness, brittleness, discoloration of pilus ;which consequence in frizzy hair ,split ends , pilus thinning. UV rays cause degradation of hair protein and pilus pigment which volition produces above mentioned hair issues. Vitamin East helps to retain the strength and vitality of hair [18] . Vitamin E decreases production of PGE2 and nitric oxide; prevents sunburn prison cell formation, ultraviolet (UV) B-induced lipid peroxidation and edema,[19,20]; which gives epidermal protection from oxidative stress. Vitamin Eastward also has a role in photograph adduct formation and allowed-suppression [21].
vi. Repairing of pilus scalp: Reduce inflammation (act as an anti-inflammatory action) on the scalp acquired past dandruff and psoriasis [22], and provide workout effect by cure dry hair and split stop bug.

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Table No.01: Vitamin East contacting Natural oil

Name of Natural Oil	Vitamin E content in oil ( mg per 100 gm )
Wheat Germ Oil	150 mg
Sunflower Oil	41 mg
Safflower Oil	34 mg
Almond Oil	39 mg
Hazelnut Oil	47 mg
Palm Oil	15 mg
Olive Oil	14 mg
Canola Oil	22 mg
Soybean Oil	12 mg
Corn Oil	15 mg
Grapeseed  Oil	29 mg
Rice bran Oil	32 mg
Babassu Oil	xix mg
Flaxseed Oil	17 mg
Peanut Oil	16 mg
Oat Oil	14 mg
Poppyseed Oil	eleven mg
Apricot Kernel Oil	4 mg
Palm Kernel Oil	four mg
Body of water Buckthorn Oil	180 mg
Argan oil	73 mg
Pine nut Oil	ix.three mg
Cod Liver oil	12.iii mg
Cotton seed oil	5 mg
Hempseed	v mg
Basil Oil	7.38 mg
Maize oil	11 mg
Palm oil	26 mg

Tabular array No.02: Marketed Preparation contacting vitamin Due east

Proper name of Production	Proper noun of Manufacturer
Vitamin E Capsules	Pfyton Remedies Hyderabad, Bharat
JASON Vitamin Due east 5,000 IU	@2013 THE HAIN Angelic Grouping,INC U.s.a.
Highgrow Hair Supplement (Biotin, CoQ-10 & Vitamin E) tablets	WEST Declension PHARMA
HealthVit E-Vitan Vitamin E Hair Oil	West Coast Pharmaceuticals works ltd, Ahmedabad, India
OGX Healing + Vitamin E Penetrating Oil, 3.3 oz, Pilus Oil for Dry or Damaged Hair	OGX U.s.
Difeel Vitamin E Oil Premium Natural Hair Oil
HAIR OIL ENRICHED WITH ARGAN OIL, AVOCADO, MACADAMIA NUT OILS, Vit. A, C, Eastward, and Pro-Vit. B5. Professional hair treatment serum	Bali Secrete
Pilus Serum, Hair Vitamins with Argan Oil, Macadamia and Avocado Oils, Vit A, C, Eastward, Pro Vit.B5, 50 Capsules Oil	Hong kong perfect link corrective express Hong Kong
Castor Oil (16oz) USDA Organic Cold-Pressed	Mary Talor naturals
Castor Oil (4oz) USDA Certified Organic	Rejuve Naturals
Lorenzo Regenerating Shampoo Ginseng Exract Plus Vitamin E for Pilus Growth 33oz	Lorenzo
Organic Castor Oil - four oz - 100% Pure, Unrefined, Cold Pressed & Hexane Free	Delux Botanicals
Vitamin Eastward Oil	GreatFull Pare
Vitamin Due east Jojoba Oil	Leven Rose
Hair oil with vitamin Due east	Golden reason
Vitamin E Oil	Difeel Sunflower Mega Care
Vitamin E Oil	Kate Blanc Cosmetics United states of america
East Oil 30,000IU	Nature's Compensation
Vitamin E heighten Professional Course	Wellness property Natural product
Vitamin E Oil Blend Pure & Natural 14000IU(d-alpha tocopherol)+Jojoba Oil+Vitamin C+Coconut Oil	Mother Nature's Essentials, Usa
Trader Joe'due south Vitamin Oil E
Natural Vitamin E  Triticum Vulgare	Naissance, Neath,U.k.
Argan Oil Pilus Serum, Vitamin E Hair Serum and Aloe Vera Hair Serum	Herstlyler Hong Kong
Vitamin E oil	Bella Terra oils
Organic Brush oil dazzler enhancer	Namskara , Los angeles UK
Evion Vitamin Eastward Capsules	Merck Pharma
Super oil alloy, Caster oil, sweet almond oil, coconut oil Vitamin Due east	Mia Adora

REFERENCES:
one. Traber MG. (2006);Vitamin E;In Modern Diet in Health and Disease. 10th ed. Baltimore, MD: Lippincott Williams & Wilkins; 2006;396-411
2. Singh U, Devaraj S, Jialal I. (2005) ;Vitamin Eastward, oxidative stress, and inflammation;Annu Rev Nutr. 2005;25:151-74.
3. Institute of Medicine. Food and Nutrition Lath. Dietary Reference Intakes: Vitamin C, Vitamin E, Selenium, and Carotenoids Washington, DC: National Academy Printing, 2000
4. Summit 10 Surprising Benefits of vitamin East for your Pilus and Skin, Available on: www.consumerhealthdigest.com
v. Your Prescription for Ageless skin. Vienna: You look so young LLC; 2006
6. Traber MG, Podda M, Weber C, Thiele J, Rallis M, Packer L. (1997);Nutrition-derived and topically applied tocotrienols accumulate in peel and protect the tissue confronting ultraviolet lite-induced oxidative stress;Asia Pac J Clin Nutr.1997; Vol.6No.1);63-7
7. Shibata A, Nakagawa Chiliad, Kawakami Y, Tsuzuki T, Miyazawa T(2010) ;Suppression of gamma-tocotrienol on UVB induced inflammation in HaCaT keratinocytes and HR-i hairless mice via inflammatory mediators multiple signaling; J Agric Food Chem. 2010 Vol.9;No.58(11):7013-20
eight. Top 10 Benefits of Vitamin Eastward for hair and peel,Available on:www.top10homeremedies.com
9. Michihara A, Ogawa S, Kamizaki Y, Akasaki Thousand. (2010);Effect of-tocotrienol on melanin content and enzymes for melanin synthesis in mouse melanoma cells;Biol Pharm Bull. 2010;Vol.33 No.9;1471-6
10. Shah K.;(2018);10 Benefits of Vitamin Eastward Capsules on Skin and Pilus,Available on: https://world wide web.beautyglimpse.com
11. Takanami Y., Iwane H, Kawai Y, Shimomitsu T; (2000);Vitamin E supplementation and endurance do: are there benefits;Sports Med;2000;Vom.29No.2;73-83
12. Panel on dietetic production, nutrition and allergies; EFSA Periodical 2010;8(ten):1816]
13. Dysken MW, Sano M, Asthana S, Vertrees JE, Pallaki M, Llorente M, Love S, Schellenberg GD, McCarten JR, Malphurs J, Prieto S, Chen P,Loreck DJ, Trapp G, Bakshi RS, Mintzer JE, Heidebrink JL, Vidal-Cardona A, Arroyo 50, Cruz AR, Zachariah S, Kowall NW, Chopra MP, Craft S, Thielke S, Turvey CL, Woodman C, Monnell KA, Gordon K, Tomaska J, Segal Y, Peduzzi PN, Guarino PD;(2014)Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial; The periodical of American Medical Association; 2014;Vol1.No 311(i):33-44
14. Maria Fernanda Reis Gavazzoni Dias.;(2015)Pilus Cosmetics: An Overview;Int J Trichology;2015; Vom 7No i;ii–xv.
15. Trueb Ralph M.;(2006) ;Pharmacologic interventions in aging hairClinical interventions in aging;2006; Vol 1 No. two;121
16. Kankana Roy Jain; (2018)The hair growth elixir nosotros demand in our life-Vitamin Due east , available at:http://www.femina.in
17. Beoy Lim Ai, Wong Jia Woei, Yuen Kah Hay;(2010) Furnishings of tocotrienol supplementation on hair growth in homo volunteers;Tropical life sciences research;2010;Vol.21, No. 2; 91
18. Sebetic, Klaudija, Ines Sjerobabski Masnec, Vlatka Čavka, Darko Biljan, Ivan Krolo. (2008);UV damage of the pilus;Collegium antropologicum;2008; Vol.32, No. 2; 163-165
19. Yoshida East, Watanabe T, Takata J, Yamazaki A, Karube Y, Kobayashi Due south.(2006) Topical application of a novel, hydrophilic gamma-tocopherol derivative reduces photo- inflammation in mice peel; J Invest Dermatol; 2006;Vol.126;1633–1640
20. Beharka AA, Wu D, Serafini Yard, Meydani SN(2002); Mechanism of vitamin Due east inhibition of cyclooxygenase activity in macrophages from old mice: Part of peroxynitrite; Gratuitous Radic Biol Med;2002;Vol. 32:503–xi
21. Thiele JJ, Hsieh SN, Ekanayake-Mudiyanselage S. (2005); Vitamin E: Critical review of its current utilize in cosmetic and clinical dermatology; Dermatol Surg;2005;Vol.31:805–13
22. Jassica L E; Vitamin Eastward oil for hair growth;Available on : http://www.alopeciafree.com

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